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Wednesday, August 30, 2006-melf- Thursday, August 24, 2006Drug D presentation for journal 2 is here, but I doubt it's going to be of much help. The journal paper is much more complete. http://www.angelfire.com/linux/ashlar/journal2.ppt right click, save target as. -melf Sunday, August 20, 2006Epidemiologic Triad of Infectious Diseases - Host Definition of Epidemiology - Epidemiology is... population. Purpose of Epidemiology 1. Identify... occurence of disease. 2. Assess... preventive and therapeutic treatments. Application of Epidemiology - But... non-infectious diseases. - Added... non-disease epidemiology Risk factors - Risk factors are characteristics... Risk Factors in Infectious Diseases - Risk factor here is promiscuous behaviour - Lack of personal hygiene is a risk factor - Risk factor here is smoking Epidemiological Approach 1. Definition of the disease 2. The cause, aetiology 5. How to prevent it - AIDS stands for Acquired... - Infected pregnant women... breast feeding. - How to control it- Nucleoside analogues... protease inhibitor - How to prevent it- No vaccine. Limitations of Epidemiology 1. Association and Causation the END tasha => Structure of HIV Genus - lentivirus linear ss positive RNA genome 5' end methylated cap HIV genome organisation structural proteins - Gag, Env (cancel out Pol) regulatory proteins - Tat, Rev, Pol Virulence factors for Viruses - promote attachment Env gene - glycosylated and cleaved... Regulation of env gene - when rev deleted... protein undetectable... Attachment - cytokine receptor But why did CD4+ cells disappear? 3. Syncytia Formation Current CDC definition of AIDS - CD4 cell count below 200 the End tasha :) Wednesday, August 09, 2006We'd also like to congratulate Lau Yu Hua for getting first in Industrial Micro(Matthew module leh, difficult to score. Haha) Yay! Study for PCT people. Principles 1, 2 Subject's safety 3, 6, 7, 9 Information to start trial 4, 5 Qualification of investigator 8 Record keeping 10, 11 Study product 12 Quality control 13 -melf- Monday, August 07, 2006hey ppl! :) EBM lecture and tutorial tomorrow tuesday - dun forget to watch the bill gates video and do ur tut. MBID assignment hardcopy due. no proteomics tutorial tomorrow. proteo tut will be done together with friday's revision lecture. r & d ppl, study for stem cell test tomorrow. there is national day celebration tomorrow. compulsory for all to attend (National Education requirement). i think it's 3-6pm not sure. wed national day! =) no class, dun come to school ^.^ thursday we all have PCT test. jia you!! :) drug devt tutorial after the test at 4pm. please do ur RA approval tutorial. friday bioprocess ppl have a test, dun forget to study. friday we have proteomics revision lecture and mass tutorial. be there or be square. finally, sorry for the haphazard post. dun really haf time to do everything nicely. my stem cells, EBM and PCT awaits! =) haha tasha ^.^ Sunday, August 06, 2006-melf- Wednesday, August 02, 2006"yOU cAn nEVer waLK pASt a pOOR peRSoN aND nOT hAve aNYthiNG tO gIVE." -anonymous Tuesday, August 01, 2006so - Happy 19th Birthday!
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